Anti-beta-2 Adrenergic Receptor antibody produced in chicken, affinity isolated antibody, buffered aqueous solution

Application

Anti-β-2 Adrenergic Receptor antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

The β-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is present within a cell membrane. It reacts with adrenaline (epinephrine) as a hormone or neurotransmitter affecting muscles or organs. It may be a risk factor for chronic pain and its polymorphisms may influence labor pain. It contains a common non-synonymous single nucleotide polymorphism. Epinephrine activates ADRB2 impairing keratinocyte migration. β2-adrenoceptor pathway is essential for cardiovascular regulation.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

β-2 Adrenergic Receptor is a member of the seven-transmembrane-domain receptor family. The ADRB2 gene is mapped on the human chromosome at 5q32. β-2 Adrenergic Receptor is a seven-transmembrane protein that consists of α helices. The N-terminal is extracellular whereas the C-terminal is intracellular.

Immunogen

Immunogen Sequence: GI # 4501969, sequence 335-408

Recombinant adrenergic, β-2-, receptor, surface

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.